Products

Western Blot (Transfected lysate)

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

EPHA8

Gene Alias

EEK, HEK3, KIAA1459

Gene Description

EPH receptor A8

Omim ID

Gene Ontology

Gene Summary

This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system. [provided by RefSeq

Other Designations

EPH- and ELK-related tyrosine kinase|OTTHUMP00000002934|OTTHUMP00000002935|ephrin type-A receptor 8|hydroxyaryl-protein kinase|protein-tyrosine kinase|tyrosine-protein kinase receptor EEK|tyrosylprotein kinase