ENSA monoclonal antibody (M01A), clone 1E8
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More Files
- More Functions
Western Blot (Cell lysate)
ENSA monoclonal antibody (M01A), clone 1E8 Western Blot analysis of ENSA expression in COLO 320 HSR ( Cat # L020V1 ).
Western Blot detection against Immunogen (39.05 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant ENSA.
Immunogen
ENSA (AAH00436, 1 a.a. ~ 121 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSQKQEEENPAEETGEEKQDTQEKEGILPERAEEAKLKAKYPSLGQKPGGSDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLPSAGPDKNLVTGDHIPTPQDLPQRKSSLVTSKLAGGQVE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (39.05 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ENSA monoclonal antibody (M01A), clone 1E8 Western Blot analysis of ENSA expression in COLO 320 HSR ( Cat # L020V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — ENSA
Entrez GeneID
2029GeneBank Accession#
BC000436Protein Accession#
AAH00436Gene Name
ENSA
Gene Alias
MGC4319, MGC78563, MGC8394
Gene Description
endosulfine alpha
Omim ID
603061Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
Other Designations
OTTHUMP00000032931|OTTHUMP00000032932|OTTHUMP00000034001|OTTHUMP00000034003|OTTHUMP00000034004|OTTHUMP00000034005|OTTHUMP00000034006
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