ENG (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human ENG full-length ORF ( AAH14271, 1 a.a. - 658 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MDRGTLPLAVALLLASCSLSPTSLAETVHCDLQPVGPERDEVTYTTSQVSKGCVAQAPNAILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAYNSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPITSAAELNDPQSILLRLGQAQGSLSFCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAGPRTVTVKVELSCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLLGEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSLIQTKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSASMISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNTIEPGQQSFVQVRVSPSVSEFLLQLDSCHLDLGPEGGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVPIPKTGTLSCTVALRPKTGSQDQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAFLIGALLTAALWYIYSHTRSPSKREPVVAVAAPASSESSSTNHSIGSTQSTPCSTSSMA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
98.12
Interspecies Antigen Sequence
Mouse (71); Rat (72)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ENG
Entrez GeneID
2022GeneBank Accession#
BC014271Protein Accession#
AAH14271Gene Name
ENG
Gene Alias
CD105, END, FLJ41744, HHT1, ORW, ORW1
Gene Description
endoglin
Gene Ontology
HyperlinkGene Summary
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CD105 antigen|OTTHUMP00000022221|Osler-Rendu-Weber syndrome 1
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Interactome
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Disease
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Publication Reference
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Noninvasive Precision Screening of Prostate Cancer by Urinary Multimarker Sensor and Artificial Intelligence Analysis.
Hojun Kim, Sungwook Park, In Gab Jeong, Sang Hoon Song, Youngdo Jeong, Choung-Soo Kim, Kwan Hyi Lee.
ACS Nano 2021 Mar; 15(3):4054.
Application:Func, Human, Human urine.
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Endoglin is a novel endothelial cell specification gene.
Banerjee S, Dhara SK, Bacanamwo M.
Stem Cell Research 2012 Jan; 8(1):85.
Application:Func, Mouse, Mouse ESC line J1.
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Noninvasive Precision Screening of Prostate Cancer by Urinary Multimarker Sensor and Artificial Intelligence Analysis.
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