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Last updated: 2016/11/27

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ELAVL3 rabbit monoclonal antibody

  • Catalog # : H00001995-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human ELAVL3 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human ELAVL3 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human ELAVL3 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1995
  • Gene Name:
  • ELAVL3
  • Gene Alias:
  • DKFZp547J036,HUC,HUCL,MGC20653,PLE21
  • Gene Description:
  • ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
  • Gene Summary:
  • A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • ELAV-like protein 3,Hu antigen C,paraneoplastic cerebellar degeneration-associated antigen,paraneoplastic limbic encephalitis antigen 21
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