EIF4EBP2 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human EIF4EBP2 partial ORF ( NP_004087, 61 a.a. - 120 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
DRRNSPMAQTPPCHLPNIPGVTSPGTLIEDSKVEVNNLNNLNNHDRKHAVGDDAQFEMDI
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
32.34
Interspecies Antigen Sequence
Mouse (97); Rat (95)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — EIF4EBP2
Entrez GeneID
1979GeneBank Accession#
NM_004096Protein Accession#
NP_004087Gene Name
EIF4EBP2
Gene Alias
4EBP2, PHASII
Gene Description
eukaryotic translation initiation factor 4E binding protein 2
Omim ID
602224Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq
Other Designations
OTTHUMP00000019756|phosphorylated, heat and acid stable regulated by insulin protein II
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Interactome
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Disease
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