EIF4EBP2 monoclonal antibody (M04), clone 2G8
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More Files
- More Functions
Western Blot detection against Immunogen (32.34 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant EIF4EBP2.
Immunogen
EIF4EBP2 (NP_004087, 61 a.a. ~ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
DRRNSPMAQTPPCHLPNIPGVTSPGTLIEDSKVEVNNLNNLNNHDRKHAVGDDAQFEMDI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (95)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (32.34 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — EIF4EBP2
Entrez GeneID
1979GeneBank Accession#
NM_004096Protein Accession#
NP_004087Gene Name
EIF4EBP2
Gene Alias
4EBP2, PHASII
Gene Description
eukaryotic translation initiation factor 4E binding protein 2
Omim ID
602224Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq
Other Designations
OTTHUMP00000019756|phosphorylated, heat and acid stable regulated by insulin protein II
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Interactome
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Disease
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