EFNA1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human EFNA1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human EFNA1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human EFNA1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — EFNA1
Entrez GeneID
1942GeneBank Accession#
EFNA1Gene Name
EFNA1
Gene Alias
B61, ECKLG, EFL1, EPLG1, LERK1, TNFAIP4
Gene Description
ephrin-A1
Omim ID
191164Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq
Other Designations
OTTHUMP00000033242|OTTHUMP00000033271|eph-related receptor tyrosine kinase ligand 1|ephrin A1|immediate early response protein B61|ligand of eph-related kinase 1|tumor necrosis factor, alpha-induced protein 4
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Interactome
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Pathway
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