PHC2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PHC2 full-length
Host
Human
Theoretical MW (kDa)
35.8
Interspecies Antigen Sequence
Mouse (97); Rat (98)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PHC2 antibody (H00001912-B01) by Western Blots.
SDS-PAGE Gel
PHC2 transfected lysate.
Western Blot
Lane 1: PHC2 transfected lysate ( 35.8 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PHC2
Entrez GeneID
1912GeneBank Accession#
NM_004427Protein Accession#
NP_004418Gene Name
PHC2
Gene Alias
EDR2, HPH2, MGC163502, PH2
Gene Description
polyhomeotic homolog 2 (Drosophila)
Omim ID
602979Gene Ontology
HyperlinkGene Summary
In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000004292|OTTHUMP00000004294|early development regulator 2 (homolog of polyhomeotic 2)|early development regulator 2-like|polyhomeotic 2|polyhomeotic-like 2
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Interactome
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Disease
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