PHC2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PHC2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PHC2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PHC2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PHC2
Entrez GeneID
1912GeneBank Accession#
PHC2Gene Name
PHC2
Gene Alias
EDR2, HPH2, MGC163502, PH2
Gene Description
polyhomeotic homolog 2 (Drosophila)
Omim ID
602979Gene Ontology
HyperlinkGene Summary
In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000004292|OTTHUMP00000004294|early development regulator 2 (homolog of polyhomeotic 2)|early development regulator 2-like|polyhomeotic 2|polyhomeotic-like 2
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Interactome
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Disease
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