PHC1 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Tissue lysate)
PHC1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PHC1 expression in human colon.
Western Blot (Transfected lysate)
Western Blot analysis of PHC1 expression in transfected 293T cell line (H00001911-T03) by PHC1 MaxPab polyclonal antibody.
Lane 1: PHC1 transfected lysate(100.2 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of PHC1 transfected lysate using anti-PHC1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PHC1 purified MaxPab mouse polyclonal antibody (B01P) (H00001911-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PHC1 protein.
Immunogen
PHC1 (AAH73964.1, 1 a.a. ~ 957 a.a) full-length human protein.
Sequence
METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRVNRTLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTPAPSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQTGLPTGLTENQSGGSLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRKKMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PHC1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PHC1 expression in human colon.Western Blot (Transfected lysate)
Western Blot analysis of PHC1 expression in transfected 293T cell line (H00001911-T03) by PHC1 MaxPab polyclonal antibody.
Lane 1: PHC1 transfected lysate(100.2 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of PHC1 transfected lysate using anti-PHC1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PHC1 purified MaxPab mouse polyclonal antibody (B01P) (H00001911-B01P). -
Gene Info — PHC1
Entrez GeneID
1911GeneBank Accession#
BC073964Protein Accession#
AAH73964.1Gene Name
PHC1
Gene Alias
EDR1, HPH1, RAE28
Gene Description
polyhomeotic homolog 1 (Drosophila)
Omim ID
602978Gene Ontology
HyperlinkGene Summary
This gene is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein. [provided by RefSeq
Other Designations
Rae28-like|early development regulator 1 (homolog of polyhomeotic 1)|polyhomeotic 1-like|polyhomeotic-like 1
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Interactome
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Publication Reference
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Mutation in PHC1 implicates chromatin remodeling in primary microcephaly pathogenesis.
Awad S, Al-Dosari MS, Al-Yacoub N, Colak D, Salih MA, Alkuraya FS, Poizat C.
Human Molecular Genetics 2013 Jun; 22(11):2200.
Application：IP, WB, Human, Human lymphocyte.
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Mutation in PHC1 implicates chromatin remodeling in primary microcephaly pathogenesis.
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