EDN3 (Human) IP-WB Antibody Pair

Catalog # H00001908-PW1

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Size:1 Set
Price: USD $ 607.00
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Immunoprecipitation of EDN3 transfected lysate using mouse monoclonal anti-EDN3 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-EDN3.

  • Specification

    Product Description

    This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.

    Reactivity

    Human

    Quality Control Testing

    Immunoprecipitation-Western Blot (IP-WB)

    Immunoprecipitation of EDN3 transfected lysate using mouse monoclonal anti-EDN3 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-EDN3.

    Supplied Product

    Antibody pair set content:
    1. Antibody pair for IP: mouse monoclonal anti-EDN3 (300 ug)
    2. Antibody pair for WB: rabbit polyclonal anti-EDN3 (50 ul)

    Storage Instruction

    Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.

  • Applications

    Immunoprecipitation-Western Blot

  • Gene Info — EDN3

    Entrez GeneID

    1908

    Gene Name

    EDN3

    Gene Alias

    ET3, MGC15067, MGC61498

    Gene Description

    endothelin 3

    Omim ID

    131242 142623 209880 277580

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed. [provided by RefSeq

    Other Designations

    OTTHUMP00000031420|truncated endothelin 3

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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