EDN2 monoclonal antibody (M01), clone 3B4-1C5
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of EDN2 expression in transfected 293T cell line by EDN2 monoclonal antibody (M01), clone 3B4-1C5.
Lane 1: EDN2 transfected lysate(20 KDa).
Lane 2: Non-transfected lysate.
Western Blot detection against Immunogen (45.32 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant EDN2.
Immunogen
EDN2 (AAH34393, 1 a.a. ~ 178 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MVSVPTTWCSVALALLVALHEGKGQAAATLEQPASSSHAQGTHLRLRRCSCSSWLDKECVYFCHLDIIWVNTPEQTAPYGLGNPPRRRRRSLPRRCQCSSARDPACATFCLRRPWTEAGAVPSRKSPADVFQTGKTGATTGELLQRLRDISTVKSLFAKRQQEAMREPRSTHSRWRKR
Host
Mouse
Reactivity
Human
Isotype
IgG2b kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (45.32 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of EDN2 expression in transfected 293T cell line by EDN2 monoclonal antibody (M01), clone 3B4-1C5.
Lane 1: EDN2 transfected lysate(20 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — EDN2
Entrez GeneID
1907GeneBank Accession#
BC034393Protein Accession#
AAH34393Gene Name
EDN2
Gene Alias
ET2, PPET2
Gene Description
endothelin 2
Omim ID
131241Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. [provided by RefSeq
Other Designations
OTTHUMP00000007075|preproendothelin 2
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Pathway
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Disease
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Publication Reference
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Estrogen and progesterone regulate expression of the endothelins in the rhesus macaque endometrium.
Keator CS, Mah K, Ohm L, Slayden OD.
Human Reproduction 2011 Jul; 26(7):1715.
Application：ICC, Monkey, Uterus.
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Estrogen and progesterone regulate expression of the endothelins in the rhesus macaque endometrium.
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