EDA monoclonal antibody (M10), clone 1G4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant EDA.
Immunogen
EDA (NP_001390.1 , 245 a.a. ~ 391 a.a) partial recombinant protein.
Sequence
ENQPAVVHLQGQGSAIQVKNDLSGGVLNDWSRITMNPKVFKLHPRSGELEVLVDGTYFIYSQVEVYYINFTDFASYEVVVDEKPFLQCTRSIETGKTNYNTCYTAGVCLLKARQKIAVKMVHADISINMSKHTTFFGAIRLGEAPAS
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — EDA
Entrez GeneID
1896GeneBank Accession#
NM_001399.1Protein Accession#
NP_001390.1Gene Name
EDA
Gene Alias
ED1, ED1-A1, ED1-A2, EDA1, EDA2, HED, XHED, XLHED
Gene Description
ectodysplasin A
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000023461|OTTHUMP00000023463|X-linked anhidroitic ectodermal dysplasia protein|ectodermal dysplasia 1, anhidrotic|ectodermal dysplasia, anhidrotic (hypohydrotic)|ectodysplasin-A
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Interactome
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Pathway
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