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E2F4 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00001874-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-E2F4 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 45.54
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-E2F4 antibody (H00001874-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00001874-T01
    E2F4 transfected lysate.
    Western Blot
    QC Testing of H00001874-T01
    Lane 1: E2F4 transfected lysate ( 45.54 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 1874
  • Protein Accession#:
  • -
  • Gene Name:
  • E2F4
  • Gene Alias:
  • E2F-4
  • Gene Description:
  • E2F transcription factor 4, p107/p130-binding
  • Gene Summary:
  • The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer. [provided by RefSeq
  • Other Designations:
  • E2F transcription factor 4,p107/p130-binding protein
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