Western blot analysis of DVL3 over-expressed 293 cell line, cotransfected with DVL3 Validated Chimera RNAi ( Cat # H00001857-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with DVL3 monoclonal antibody (M04), clone 4H2 (Cat # H00001857-M04 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation. [provided by RefSeq
dishevelled 3,dishevelled 3 (homologous to Drosophila dsh)