DVL2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human DVL2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human DVL2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human DVL2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — DVL2
Entrez GeneID
1856GeneBank Accession#
DVL2Gene Name
DVL2
Gene Alias
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Gene Description
dishevelled, dsh homolog 2 (Drosophila)
Omim ID
602151Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq
Other Designations
DSH homolog 2|dishevelled 2|dishevelled 2 (homologous to Drosophila dsh)|segment polarity protein dishevelled homolog DVL-2
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