Immunoprecipitation of DVL2 transfected lysate using anti-DVL2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with DVL2 MaxPab mouse polyclonal antibody (B01) (H00001856-B01).
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq
DSH homolog 2,dishevelled 2,dishevelled 2 (homologous to Drosophila dsh),segment polarity protein dishevelled homolog DVL-2