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DUSP6 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00001848-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-DUSP6 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 42.3
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-DUSP6 antibody (H00001848-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00001848-T01
    DUSP6 transfected lysate
    Western Blot
    QC Testing of H00001848-T01
    Lane 1: DUSP6 transfected lysate ( 42.3 KDa).
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 1848
  • Gene Name:
  • DUSP6
  • Gene Alias:
  • MKP3,PYST1
  • Gene Description:
  • dual specificity phosphatase 6
  • Gene Summary:
  • The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • MAP kinase phosphatase 3,serine/threonine specific protein phosphatase
  • Gene Pathway
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