TSC22D3 monoclonal antibody (M02), clone 2B2
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant TSC22D3.
Immunogen
TSC22D3 (AAH18148, 1 a.a. ~ 77 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSCLSLEEPAPESPQVPEAPGGSAV
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.21 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TSC22D3 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — TSC22D3
Entrez GeneID
1831GeneBank Accession#
BC018148Protein Accession#
AAH18148Gene Name
TSC22D3
Gene Alias
DIP, DKFZp313A1123, DSIPI, GILZ, TSC-22R, hDIP
Gene Description
TSC22 domain family, member 3
Omim ID
300506Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene shares significant sequence identity with the murine TSC-22 and Drosophila shs, both of which are leucine zipper proteins, that function as transcriptional regulators. The expression of this gene is stimulated by glucocorticoids and interleukin 10, and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid and chemokine. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
Other Designations
DSIP-immunoreactive leucine zipper protein|OTTHUMP00000023811|OTTHUMP00000023813|OTTHUMP00000023814|TSC-22 related protein|delta sleep inducing peptide, immunoreactor|glucocorticoid-induced leucine zipper protein
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Interactome
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Disease
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Publication Reference
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Novel p65 Binding Glucocorticoid-induced Leucine Zipper Peptide Suppresses Experimental Autoimmune Encephalomyelitis.
Srinivasan M, Janardhanam S.
The Journal of Biological Chemistry 2011 Dec; 286(52):44799.
Application:ELISA, Human, CD4+ peripheral blood mononuclear cells.
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Novel p65 Binding Glucocorticoid-induced Leucine Zipper Peptide Suppresses Experimental Autoimmune Encephalomyelitis.
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