DSCR1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of RCAN1 expression in transfected 293T cell line (H00001827-T01) by RCAN1 MaxPab polyclonal antibody.
Lane 1: DSCR1 transfected lysate(12.87 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to DSCR1 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human DSCR1 protein.
Immunogen
DSCR1 (NP_981962.1, 1 a.a. ~ 117 a.a) full-length human protein.
Sequence
MKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQEKEEEEEMERMRRPKPKIIQTRRPEYTPIHLS
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of RCAN1 expression in transfected 293T cell line (H00001827-T01) by RCAN1 MaxPab polyclonal antibody.
Lane 1: DSCR1 transfected lysate(12.87 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to DSCR1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — RCAN1
Entrez GeneID
1827GeneBank Accession#
NM_203417.1Protein Accession#
NP_981962.1Gene Name
RCAN1
Gene Alias
ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1
Gene Description
regulator of calcineurin 1
Omim ID
602917Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Down syndrome candidate region 1|Down syndrome critical region gene 1|calcipressin 1|calcium and oxidant-inducible mRNA|modulatory calcineurin-interacting protein 1|myocyte-enriched calcineurin-interacting protein 1|near DSCR proline-rich protein
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Interactome
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Disease
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