DSC2 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of DSC2 transfected lysate using rabbit polyclonal anti-DSC2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-DSC2.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of DSC2 transfected lysate using rabbit polyclonal anti-DSC2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-DSC2.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-DSC2 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-DSC2 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — DSC2
Entrez GeneID
1824Gene Name
DSC2
Gene Alias
ARVD11, CDHF2, DG2, DGII/III, DKFZp686I11137, DSC3
Gene Description
desmocollin 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
desmosomal glycoprotein II/III
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Interactome
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Pathway
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Disease
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