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DR1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00001810-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-DR1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 19.47
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-DR1 antibody (H00001810-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00001810-T01
    DR1 transfected lysate.
    Western Blot
    QC Testing of H00001810-T01
    Lane 1: DR1 transfected lysate ( 19.47 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 1810
  • Gene Name:
  • DR1
  • Gene Alias:
  • NC2,NC2-BETA
  • Gene Description:
  • down-regulator of transcription 1, TBP-binding (negative cofactor 2)
  • Gene Summary:
  • This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000012556,OTTHUMP00000012557,down-regulator of transcription 1
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