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Last updated: 2017/3/19

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DR1 Pre-design Chimera RNAi

  • Catalog # : H00001810-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens down-regulator of transcription 1, TBP-binding (negative cofactor 2) (DR1), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_001938
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 1810
  • Gene Name:
  • DR1
  • Gene Alias:
  • NC2,NC2-BETA
  • Gene Description:
  • down-regulator of transcription 1, TBP-binding (negative cofactor 2)
  • Gene Summary:
  • This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000012556,OTTHUMP00000012557,down-regulator of transcription 1
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