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Last updated: 2017/8/13
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DR1 polyclonal antibody (A01)

  • Catalog # : H00001810-A01
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length recombinant DR1.
  • Immunogen:
  • DR1 (AAH02809, 1 a.a. ~ 176 a.a) full-length recombinant protein with GST tag.
  • Sequence:
  • MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEEDDDDI
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00001810-A01
    Western Blot detection against Immunogen (45.47 KDa) .
  • Storage Buffer:
  • 50 % glycerol
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1810
  • Gene Name:
  • DR1
  • Gene Alias:
  • NC2,NC2-BETA
  • Gene Description:
  • down-regulator of transcription 1, TBP-binding (negative cofactor 2)
  • Gene Summary:
  • This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000012556,OTTHUMP00000012557,down-regulator of transcription 1
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