DPYS monoclonal antibody (M01), clone 3B1
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant DPYS.
Immunogen
DPYS (NP_001376, 422 a.a. ~ 519 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
AVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged DPYS is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — DPYS
Entrez GeneID
1807GeneBank Accession#
NM_001385Protein Accession#
NP_001376Gene Name
DPYS
Gene Alias
DHP, DHPase
Gene Description
dihydropyrimidinase
Omim ID
222748Gene Ontology
HyperlinkGene Summary
Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria. [provided by RefSeq
Other Designations
dihydropyrimidine amidohydrolase|hydantoinase
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Interactome
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Pathway
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Disease
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