DPYD DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human DPYD DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDNPLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATETLILAFSLMNHL
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — DPYD
Entrez GeneID
1806GeneBank Accession#
BC008379.1Protein Accession#
AAH08379Gene Name
DPYD
Gene Alias
DHP, DHPDHASE, DPD, MGC132008, MGC70799
Gene Description
dihydropyrimidine dehydrogenase
Omim ID
274270Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000037640|OTTHUMP00000058954|dihydrothymine dehydrogenase|dihydrouracil dehydrogenase
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Interactome
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Pathway
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Disease
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