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Last updated: 2019/9/15

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DPYD monoclonal antibody (M01J), clone 7D4 CX Grade

  • Catalog # : H00001806-M01J
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a partial recombinant DPYD.
  • Immunogen:
  • DPYD (NP_000101, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
  • Sequence:
  • MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYY
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Isotype:
  • IgG1 Kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00001806-M01J
    Western Blot detection against Immunogen (37.84 KDa) .
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Immunofluorescence
  • Immunofluorescence enlargeenlarge this image
  • Immunofluorescence of monoclonal antibody to DPYD on HeLa cell . [antibody concentration 10 ug/ml]
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1806
  • Gene Name:
  • DPYD
  • Gene Alias:
  • DHP,DHPDHASE,DPD,MGC132008,MGC70799
  • Gene Description:
  • dihydropyrimidine dehydrogenase
  • Gene Summary:
  • The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000037640,OTTHUMP00000058954,dihydrothymine dehydrogenase,dihydrouracil dehydrogenase
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