DPAGT1 monoclonal antibody (M04), clone 1G1
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant DPAGT1.
Immunogen
DPAGT1 (NP_001373, 296 a.a. ~ 377 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
IIPCPRHRIPRLNIKTGKLEMSYSKFKTKSLSFLGTFILKVAESLQLVTVHQSETEDGEFTECNNMTLINLLLKVLGPIHER
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (89)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged DPAGT1 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — DPAGT1
Entrez GeneID
1798GeneBank Accession#
NM_001382Protein Accession#
NP_001373Gene Name
DPAGT1
Gene Alias
ALG7, CDG-Ij, D11S366, DGPT, DPAGT, DPAGT2, G1PT, GPT, UAGT, UGAT
Gene Description
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. This enzyme belongs to the glycosyltransferase family 4. This protein is an integral membrane protein of the endoplasmic reticulum. The congenital disorder of glycosylation type Ij is caused by mutation in the gene encoding this enzyme. [provided by RefSeq
Other Designations
GlcNAc-1-P transferase|N-acetylglucosamine-1-phosphate transferase|UDP-GlcNAc:dolichyl-phosphate N-acetylglucosaminephosphotransferase|UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase|dolichyl-phosphate alpha-N-acetylglucos
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Interactome
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Pathway
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Disease
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