DOK1 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of DOK1 transfected lysate using rabbit polyclonal anti-DOK1 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-DOK1.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of DOK1 transfected lysate using rabbit polyclonal anti-DOK1 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-DOK1.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-DOK1 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-DOK1 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — DOK1
Entrez GeneID
1796Gene Name
DOK1
Gene Alias
MGC117395, MGC138860, P62DOK
Gene Description
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
Omim ID
602919Gene Ontology
HyperlinkGene Summary
Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling. [provided by RefSeq
Other Designations
Downstream of tyrosine kinase 1|docking protein 1|docking protein 1 (downstream of tyrosine kinase 1)|docking protein 1, 62kD (downstream of tyrosine kinase 1)
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Interactome
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Disease
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