DOCK1 monoclonal antibody (M02), clone 3D10
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant DOCK1.
Immunogen
DOCK1 (NP_001371, 698 a.a. ~ 803 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LETYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDMMSSMSDQTVRVKGAALKYLPT
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
DOCK1 monoclonal antibody (M02), clone 3D10. Western Blot analysis of DOCK1 expression in human colon.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged DOCK1 is 10 ng/ml as a capture antibody.ELISA
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Gene Info — DOCK1
Entrez GeneID
1793GeneBank Accession#
NM_001380Protein Accession#
NP_001371Gene Name
DOCK1
Gene Alias
DOCK180, ced5
Gene Description
dedicator of cytokinesis 1
Omim ID
601403Gene Ontology
HyperlinkGene Summary
This gene product binds to the SH3 domain of CRK protein. It may regulate cell surface extension and may have a role in the cell surface extension of an engulfing cell around a dying cell during apoptosis. [provided by RefSeq
Other Designations
dedicator of cyto-kinesis 1
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Interactome
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Pathway
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Disease
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