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Last updated: 2016/10/23

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DNTT rabbit monoclonal antibody

  • Catalog # : H00001791-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human DNTT peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human DNTT is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human DNTT peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 1791
  • GeneBank Accession#:
  • DNTT
  • Gene Name:
  • DNTT
  • Gene Alias:
  • TDT
  • Gene Description:
  • deoxynucleotidyltransferase, terminal
  • Gene Summary:
  • This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq
  • Other Designations:
  • DNA nucleotidylexotransferase,OTTHUMP00000020171,nucleosidetriphosphate:DNA deoxynucleotidylexotransferase,terminal addition enzyme,terminal deoxynucleotidyltransferase,terminal deoxyribonucleotidyltransferase,terminal transferase
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