DNMT3A (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of DNMT3A transfected lysate using rabbit polyclonal anti-DNMT3A and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-DNMT3A.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of DNMT3A transfected lysate using rabbit polyclonal anti-DNMT3A and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-DNMT3A.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-DNMT3A (300 ul)
2. Antibody pair for WB: mouse polyclonal anti-DNMT3A (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — DNMT3A
Entrez GeneID
1788Gene Name
DNMT3A
Gene Alias
DNMT3A2, M.HsaIIIA
Gene Description
DNA (cytosine-5-)-methyltransferase 3 alpha
Omim ID
602769Gene Ontology
HyperlinkGene Summary
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
DNA MTase HsaIIIA|DNA cytosine methyltransferase 3 alpha|DNA cytosine methyltransferase 3A2|DNA methyltransferase HsaIIIA|OTTHUMP00000120005|OTTHUMP00000120006
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Interactome
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Pathway
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Disease
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