DNMT2 monoclonal antibody (M01), clone 1E12
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant DNMT2.
Immunogen
DNMT2 (AAH47733, 1 a.a. ~ 391 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFHHTQLLAKTIEGITLEEFDRLSFDMILMSPPCQPFTRIGRQGDMTDSRTNSFLYILDILPRLQKLPKYILLENVKGFEVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMDVEEKIQEKNVEPNISFDGSIQCSGKDAILFKLETAEEIHRKNQQDSDLSVKMLKDFLEDDTDVNQYLLPPKSLLRYALLLDIVQPTCRRSVCFTKGYGSYIEGTGSVLQTAEDVQVENIYKSLTNLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGFPEKITVKQRYRLLGNSLNVHVVAKLIKILYE
Host
Mouse
Reactivity
Human
Isotype
IgG1 lambda
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (68.75 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
DNMT2 monoclonal antibody (M01), clone 1E12 Western Blot analysis of DNMT2 expression in Hela S3 NE ( Cat # L013V3 ).Western Blot (Transfected lysate)
Western Blot analysis of DNMT2 expression in transfected 293T cell line by DNMT2 monoclonal antibody (M01), clone 1E12.
Lane 1: DNMT2 transfected lysate(45 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to DNMT2 on HeLa cell. [antibody concentration 40 ug/ml] -
Gene Info — TRDMT1
Entrez GeneID
1787GeneBank Accession#
BC047733Protein Accession#
AAH47733Gene Name
TRDMT1
Gene Alias
DNMT2, M.HsaIIP, PuMet, RNMT1
Gene Description
tRNA aspartic acid methyltransferase 1
Omim ID
602478Gene Ontology
HyperlinkGene Summary
This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
DNA (cytosine-5-)-methyltransferase 2|DNA MTase homolog HsaIIP|DNA methyltransferase homolog HsaIIP|DNA methyltransferase-2|OTTHUMP00000019228|OTTHUMP00000045198|tRNA aspartic acid methyltransferase 1 variant 1|tRNA aspartic acid methyltransferase 1 varia
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Interactome
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Pathway
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Disease
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