DNASE2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of DNASE2 expression in transfected 293T cell line (H00001777-T01) by DNASE2 MaxPab polyclonal antibody.
Lane 1: DNASE2 transfected lysate(39.6 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to DNASE2 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human DNASE2 protein.
Immunogen
DNASE2 (NP_001366.1, 1 a.a. ~ 360 a.a) full-length human protein.
Sequence
MIPLLLAALLCVPAGALTCYGDSGQPVDWFVVYKLPALRGSGEAAQRGLQYKYLDESSGGWRDGRALINSPEGAVGRSLQPLYRSNTSQLAFLLYNDQPPQPSKAQDSSMRGHTKGVLLLDHDGGFWLVHSVPNFPPPASSAAYSWPHSACTYGQTLLCVSFPFAQFSKMGKQLTYTYPWVYNYQLEGIFAQEFPDLENVVKGHHVSQEPWNSSITLTSQAGAVFQSFAKFSKFGDDLYSGWLAAALGTNLQVQFWHKTVGILPSNCSDIWQVLNVNQIAFPGPAGPSFNSTEDHSKWCVSPKGPWTCVGDMNRNQGEEQRGGGTLCAQLPALWKAFQPLVKNYQPCNGMARKPSRAYKI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (72); Rat (73)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of DNASE2 expression in transfected 293T cell line (H00001777-T01) by DNASE2 MaxPab polyclonal antibody.
Lane 1: DNASE2 transfected lysate(39.6 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to DNASE2 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — DNASE2
Entrez GeneID
1777GeneBank Accession#
NM_001375Protein Accession#
NP_001366.1Gene Name
DNASE2
Gene Alias
DNASE2A, DNL, DNL2
Gene Description
deoxyribonuclease II, lysosomal
Omim ID
126350Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq
Other Designations
DNase II alpha|DNase II, lysosomal|R31240_2|acid DNase
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Interactome
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Pathway
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Disease
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