DNASE2 polyclonal antibody (A01)
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More Files
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Western Blot (Cell lysate)
DNASE2 polyclonal antibody (A01), Lot # 051024JC01 Western Blot analysis of DNASE2 expression in MES-SA/Dx5 ( Cat # L021V1 ).
Western Blot detection against Immunogen (37.11 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant DNASE2.
Immunogen
DNASE2 (NP_001366, 261 a.a. ~ 360 a.a) partial recombinant protein with GST tag.
Sequence
GILPSNCSDIWQVLNVNQIAFPGPAGPSFNSTEDHSKWCVSPKGPWTCVGDMNRNQGEEQRGGGTLCAQLPALWKAFQPLVKNYQPCNGMARKPSRAYKI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (68); Rat (69)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
DNASE2 polyclonal antibody (A01), Lot # 051024JC01 Western Blot analysis of DNASE2 expression in MES-SA/Dx5 ( Cat # L021V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — DNASE2
Entrez GeneID
1777GeneBank Accession#
NM_001375Protein Accession#
NP_001366Gene Name
DNASE2
Gene Alias
DNASE2A, DNL, DNL2
Gene Description
deoxyribonuclease II, lysosomal
Omim ID
126350Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq
Other Designations
DNase II alpha|DNase II, lysosomal|R31240_2|acid DNase
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Interactome
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Pathway
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Disease
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