DMRT1 (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human DMRT1 full-length ORF ( AAH40847.1, 1 a.a. - 373 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MPNDEAFSKPSTPSEAPHAPGVPPQGRAGGFGKASGALVGAASGSSAGGSSRGGGSGSGASDLGAGSKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEELGISHPIPLPSAAELLVKRENNGSNPCLMTECSGTSQPPPASVPTTAASEGRMVIQDIPAVTSRGHVENTPDLVSDSTYYSSFYQPSLFPYYNNLYNCPQYSMALAADSASGEVGNPLGGSPVKNSLRGLPGPYVPGQTGNQWQMKNMENRHAMSSQYRMHSYYPPPSYLGQSVPQFFTFEDAPSYPEARASVFSPPSSQDSGLVSLSSSSPISNKSTKAVLECEPASEPSSFTVTPVIEEDE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
66.77
Interspecies Antigen Sequence
Mouse (81); Rat (80)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — DMRT1
Entrez GeneID
1761GeneBank Accession#
BC040847Protein Accession#
AAH40847.1Gene Name
DMRT1
Gene Alias
DMT1
Gene Description
doublesex and mab-3 related transcription factor 1
Omim ID
602424Gene Ontology
HyperlinkGene Summary
This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq
Other Designations
DM domain expressed in testis 1|OTTHUMP00000020961
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Interactome
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Disease
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