DMRT1 monoclonal antibody (M01), clone 1G11
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More Files
- More Functions
Western Blot (Cell lysate)
DMRT1 monoclonal antibody (M01), clone 1G11 Western Blot analysis of DMRT1 expression in HL-60 ( Cat # L014V1 ).
Western Blot (Transfected lysate)
Western Blot analysis of DMRT1 expression in transfected 293T cell line by DMRT1 monoclonal antibody (M01), clone 1G11.
Lane 1: DMRT1 transfected lysate(39.5 KDa).
Lane 2: Non-transfected lysate.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged DMRT1 is approximately 0.3ng/ml as a capture antibody.
Western Blot detection against Immunogen (66.77 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant DMRT1.
Immunogen
DMRT1 (AAH40847.1, 1 a.a. ~ 373 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MPNDEAFSKPSTPSEAPHAPGVPPQGRAGGFGKASGALVGAASGSSAGGSSRGGGSGSGASDLGAGSKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEELGISHPIPLPSAAELLVKRENNGSNPCLMTECSGTSQPPPASVPTTAASEGRMVIQDIPAVTSRGHVENTPDLVSDSTYYSSFYQPSLFPYYNNLYNCPQYSMALAADSASGEVGNPLGGSPVKNSLRGLPGPYVPGQTGNQWQMKNMENRHAMSSQYRMHSYYPPPSYLGQSVPQFFTFEDAPSYPEARASVFSPPSSQDSGLVSLSSSSPISNKSTKAVLECEPASEPSSFTVTPVIEEDE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (81); Rat (80)
Isotype
IgG1 kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (66.77 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
DMRT1 monoclonal antibody (M01), clone 1G11 Western Blot analysis of DMRT1 expression in HL-60 ( Cat # L014V1 ).Western Blot (Transfected lysate)
Western Blot analysis of DMRT1 expression in transfected 293T cell line by DMRT1 monoclonal antibody (M01), clone 1G11.
Lane 1: DMRT1 transfected lysate(39.5 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged DMRT1 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — DMRT1
Entrez GeneID
1761GeneBank Accession#
BC040847Protein Accession#
AAH40847.1Gene Name
DMRT1
Gene Alias
DMT1
Gene Description
doublesex and mab-3 related transcription factor 1
Omim ID
602424Gene Ontology
HyperlinkGene Summary
This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq
Other Designations
DM domain expressed in testis 1|OTTHUMP00000020961
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Interactome
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Disease
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