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DMPK 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00001760-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-DMPK full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 69.3
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-DMPK antibody (H00001760-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00001760-T01
    DMPK transfected lysate.
    Western Blot
    QC Testing of H00001760-T01
    Lane 1: DMPK transfected lysate ( 69.3 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 1760
  • Gene Name:
  • DMPK
  • Gene Alias:
  • DM,DM1,DM1PK,DMK,MDPK,MT-PK
  • Gene Description:
  • dystrophia myotonica-protein kinase
  • Gene Summary:
  • The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
  • Other Designations:
  • DM protein kinase,dystrophia myotonica 1,myotonic dystrophy associated protein kinase,myotonic dystrophy protein kinase,myotonin protein kinase A,thymopoietin homolog
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