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DMPK (Human) IP-WB Antibody Pair

  • Catalog # : H00001760-PW1
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00001760-PW1
    Immunoprecipitation of DMPK transfected lysate using rabbit polyclonal anti-DMPK and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-DMPK.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-DMPK (300 ul)
    2. Antibody pair for WB: mouse purified polyclonal anti-DMPK (50 ug)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Entrez GeneID:
  • 1760
  • Gene Name:
  • DMPK
  • Gene Alias:
  • DM,DM1,DM1PK,DMK,MDPK,MT-PK
  • Gene Description:
  • dystrophia myotonica-protein kinase
  • Gene Summary:
  • The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
  • Other Designations:
  • DM protein kinase,dystrophia myotonica 1,myotonic dystrophy associated protein kinase,myotonic dystrophy protein kinase,myotonin protein kinase A,thymopoietin homolog
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