DLST polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant DLST.
Immunogen
DLST (NP_001924, 1 a.a. ~ 99 a.a) partial recombinant protein with GST tag.
Sequence
MLSRSRCVSRAFSRSLSAFQKGNCPLGRRSLPGVSLCQGPGYPNSRKVVINNSVFSVRFFRTTAVCKDDLVTVKTPAFAESVTEGDVRWEKAVGDTVAE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (91)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
DLST polyclonal antibody (A01), Lot # 060803QCS1. Western Blot analysis of DLST expression in U-2 OS.Western Blot (Cell lysate)
DLST polyclonal antibody (A01), Lot # 051123JC01 Western Blot analysis of DLST expression in HeLa ( Cat # L013V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — DLST
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Interactome
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Pathway
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Citrate cycle (TCA cycle)
- Lysine degradation
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Disease
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Publication Reference
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DLST-dependence dictates metabolic heterogeneity in TCA-cycle usage among triple-negative breast cancer.
Ning Shen, Sovannarith Korm, Theodoros Karantanos, Dun Li, Xiaoyu Zhang, Eleni Ritou, Hanfei Xu, Andrew Lam, Justin English, Wei-Xing Zong, Ching-Ti Liu, Orian Shirihai, Hui Feng.
Communications Biology 2021 Nov; 4(1):1289.
Application:WB-Ce, WB-Tr, Human, BT-549, CAMA-1, HCC1428, HCC1806, Hs 578T, MCF-7, MCF 10A, MDA-MB-231, MDA-MB-436, SUM159PT, T-47D, ZR-75-1 cells.
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DLST-dependence dictates metabolic heterogeneity in TCA-cycle usage among triple-negative breast cancer.
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