DHPS purified MaxPab mouse polyclonal antibody (B02P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human DHPS protein.
Immunogen
DHPS (NP_001921.1, 1 a.a. ~ 369 a.a) full-length human protein.
Sequence
MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFGRAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLVQHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFEDWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGSLGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGADYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMDAFMHEKNED
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (91); Rat (92)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
DHPS MaxPab polyclonal antibody. Western Blot analysis of DHPS expression in human placenta.Western Blot (Transfected lysate)
Western Blot analysis of DHPS expression in transfected 293T cell line (H00001725-T01) by DHPS MaxPab polyclonal antibody.
Lane 1: DHPS transfected lysate(40.59 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — DHPS
Entrez GeneID
1725GeneBank Accession#
NM_001930Protein Accession#
NP_001921.1Gene Name
DHPS
Gene Alias
MIG13
Gene Description
deoxyhypusine synthase
Omim ID
600944Gene Ontology
HyperlinkGene Summary
The unusual amino acid hypusine is formed posttranslationally and is only found in a single cellular protein, eukaryotic translation initiation factor 5A. In the first step of hypusine biosynthesis, deoxyhypusine synthase catalyzes the NAD-dependent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the EIF5A precursor protein to form the intermediate deoxyhypusine residue. This gene consists of nine exons spanning 6.6 kb. Three transcript variants have been isolated. However, only transcript variant 1 encodes an active protein. The shorter variants may act as modulating factors of DHPS activity. [provided by RefSeq
Other Designations
migration-inducing gene 13
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