DHFR MaxPab mouse polyclonal antibody (B01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human DHFR protein.
Immunogen
DHFR (XP_937759.1, 1 a.a. ~ 187 a.a) full-length human protein.
Sequence
MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of DHFR expression in transfected 293T cell line (H00001719-T01) by DHFR MaxPab polyclonal antibody.
Lane 1: DHFR transfected lysate(20.57 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to DHFR on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — DHFR
Entrez GeneID
1719GeneBank Accession#
NM_000791.3Protein Accession#
XP_937759.1Gene Name
DHFR
Gene Alias
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Gene Description
dihydrofolate reductase
Omim ID
126060Gene Ontology
HyperlinkGene Summary
Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. [provided by RefSeq
Other Designations
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Interactome
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