DFNA5 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human DFNA5 peptide using ARM Technology.
Immunogen
A synthetic peptide of human DFNA5 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human DFNA5 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — DFNA5
Entrez GeneID
1687GeneBank Accession#
DFNA5Gene Name
DFNA5
Gene Alias
ICERE-1
Gene Description
deafness, autosomal dominant 5
Gene Ontology
HyperlinkGene Summary
Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
deafness, autosomal dominant 5 protein|inversely correlated with estrogen receptor expression 1|nonsyndromic hearing impairment protein
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Interactome
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Disease
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