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TIMM8A Pre-design Chimera RNAi

  • Catalog # : H00001678-R01
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  • Specification
  • Product Description:
  • Homo sapiens translocase of inner mitochondrial membrane 8 homolog A (yeast) (TIMM8A), nuclear gene encoding mitochondrial protein, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_004085
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 1678
  • Gene Name:
  • TIMM8A
  • Gene Alias:
  • DDP,DDP1,DFN1,MGC12262,MTS
  • Gene Description:
  • translocase of inner mitochondrial membrane 8 homolog A (yeast)
  • Gene Summary:
  • This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms
  • Other Designations:
  • OTTHUMP00000023681,deafness/dystonia peptide,translocase of inner mitochondrial membrane 8 homolog A
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