TIMM8A monoclonal antibody (M04), clone 1A12

Catalog # H00001678-M04

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Size:100 ug
Price: USD $ 335.00
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  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Sandwich ELISA (Recombinant protein)
Application

Sandwich ELISA (Recombinant protein)

Detection limit for recombinant GST tagged TIMM8A is 1 ng/ml as a capture antibody.

QC Test

Western Blot detection against Immunogen (33.66 KDa) .

  • Specification

    Product Description

    Mouse monoclonal antibody raised against a full-length recombinant TIMM8A.

    Immunogen

    TIMM8A (AAH05236, 1 a.a. ~ 72 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Sequence

    MLLNDKWVNEEIKKKIEKCLETNDNGNTTYQNLWDTAKAVVRGKFIAISTYIKKEEKLQINNLTMNLIELEN

    Host

    Mouse

    Reactivity

    Human

    Isotype

    IgG2a Kappa

    Quality Control Testing

    Antibody Reactive Against Recombinant Protein.

    Western Blot detection against Immunogen (33.66 KDa) .

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Recombinant protein)

    Sandwich ELISA (Recombinant protein)

    Detection limit for recombinant GST tagged TIMM8A is 1 ng/ml as a capture antibody.

    ELISA

  • Gene Info — TIMM8A

    Entrez GeneID

    1678

    GeneBank Accession#

    BC005236

    Protein Accession#

    AAH05236

    Gene Name

    TIMM8A

    Gene Alias

    DDP, DDP1, DFN1, MGC12262, MTS

    Gene Description

    translocase of inner mitochondrial membrane 8 homolog A (yeast)

    Omim ID

    300356 304700 311150

    Gene Ontology

    Hyperlink

    Gene Summary

    This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms

    Other Designations

    OTTHUMP00000023681|deafness/dystonia peptide|translocase of inner mitochondrial membrane 8 homolog A

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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