CFD monoclonal antibody (M02), clone 5F20
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CFD.
Immunogen
CFD (NP_001919.2, 154 a.a. ~ 253 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (64); Rat (68)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CFD is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — CFD
Entrez GeneID
1675GeneBank Accession#
NM_001928.2Protein Accession#
NP_001919.2Gene Name
CFD
Gene Alias
ADIPSIN, ADN, DF, PFD
Gene Description
complement factor D (adipsin)
Omim ID
134350Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. [provided by RefSeq
Other Designations
C3 convertase activator|D component of complement (adipsin)|complement factor D|complement factor D preproprotein|properdin factor D
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Interactome
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Pathway
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Disease
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