DEFA5 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human DEFA5 full-length ORF ( NP_066290.1, 1 a.a. - 94 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MRTIAILAAILLVALQAQAESLQERADEATTQKQSGEDNQDLAISFAGNGLSALRTSGSQARATCYCRTGRCATRESLSGVCEISGRLYRLCCR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.5
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — DEFA5
Entrez GeneID
1670GeneBank Accession#
NM_021010.1Protein Accession#
NP_066290.1Gene Name
DEFA5
Gene Alias
DEF5, HD-5, MGC129728
Gene Description
defensin, alpha 5, Paneth cell-specific
Omim ID
600472Gene Ontology
HyperlinkGene Summary
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum. [provided by RefSeq
Other Designations
defensin 5|defensin, alpha 5|defensin, alpha 5, preproprotein
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Interactome
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