DEFA1 monoclonal antibody (M03), clone 1B20
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant DEFA1.
Immunogen
DEFA1 (AAH27917, 1 a.a. ~ 94 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGSRKSMDCYCRIPACIAGERRYGTCIYQGRLWAFCC
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — DEFA1
Entrez GeneID
1667GeneBank Accession#
BC027917Protein Accession#
AAH27917Gene Name
DEFA1
Gene Alias
DEF1, DEFA2, HNP-1, HP-1, MGC138393, MRS
Gene Description
defensin, alpha 1
Omim ID
125220Gene Ontology
HyperlinkGene Summary
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. It differs from defensin, alpha 3 by only one amino acid. [provided by RefSeq
Other Designations
OTTHUMP00000196017|defensin, alpha 1, myeloid-related sequence|defensin, alpha 2|myeloid-related sequence
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