DDC 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-DDC full-length
Host
Human
Theoretical MW (kDa)
52.91
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-DDC antibody (H00001644-B02) by Western Blots.
SDS-PAGE Gel
DDC transfected lysate.
Western Blot
Lane 1: DDC transfected lysate ( 52.91 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — DDC
Entrez GeneID
1644GeneBank Accession#
NM_000790.2Protein Accession#
NP_000781.1Gene Name
DDC
Gene Alias
AADC
Gene Description
dopa decarboxylase (aromatic L-amino acid decarboxylase)
Gene Ontology
HyperlinkGene Summary
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
L-Dopa decarboxylase|aromatic L-amino acid decarboxylase
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Interactome
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Pathway
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Disease
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