DDC monoclonal antibody (M18), clone 8E8
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of DDC expression in transfected 293T cell line by DDC monoclonal antibody (M18), clone 8E8.
Lane 1: DDC transfected lysate (Predicted MW: 53.9 KDa).
Lane 2: Non-transfected lysate.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged DDC is 0.03 ng/ml as a capture antibody.
Western Blot detection against Immunogen (78.43 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant DDC.
Immunogen
DDC (AAH08366, 1 a.a. ~ 480 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (78.43 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of DDC expression in transfected 293T cell line by DDC monoclonal antibody (M18), clone 8E8.
Lane 1: DDC transfected lysate (Predicted MW: 53.9 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged DDC is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — DDC
Entrez GeneID
1644GeneBank Accession#
BC008366.1Protein Accession#
AAH08366Gene Name
DDC
Gene Alias
AADC
Gene Description
dopa decarboxylase (aromatic L-amino acid decarboxylase)
Gene Ontology
HyperlinkGene Summary
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
L-Dopa decarboxylase|aromatic L-amino acid decarboxylase
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Interactome
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Pathway
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Disease
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